pneumothorax, birt hogg dube syndrome, renal cell carcinoma
Conditions
Interventions
lab, CT, questionnaire
Sponsors
SFOH
Eligibility
Inclusion criteria
Inclusion criteria: - Able to give written informed consent prior to participation in the study. Subjects must be able to read, comprehend and write at a level sufficient to complete study related materials. - Subjects must have a diagnosis of spontaneous pneumothorax (this might be a 2nd PSP if not proven to be related to a known disease or the first contralateral pneumothorax) - Age: at least 16 years of age at visit 1 - Sex: male or female
Exclusion criteria
Exclusion criteria: - Age under 16 - Subjects with claustrophobia making it impossible to perform a CT scan - Has a history or current evidence of any condition, therapy, or laboratory abnormality that might confound the results of the trial, interfere with the subject’s participation for the full duration of the trial, or it is not in the best interest of the subject to participate, in the opinion of the treating investigator. - A CT scan of the thorax is already been performed within a year before the PSP - lung carcinoma - lung metastases - Iatrogenic pneumothorax - secondary spontaneous pneumothorax
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| The prevalence of BHD syndrome based on mutation testing in a cohort of patients with PSP Other (CT-) abnormalities that are likely related to the cause of PSP | — |
Primary
| Measure | Time frame |
|---|---|
| The prevalence of CT abnormalities possibly related to Birt-Hogg-Dubé syndrome in subjects presenting with a 'primary' spontaneous pneumothorax. | — |
Contacts
Public Contactbart hoppe
lumc
Outcome results
None listed