eating behaviour
Conditions
Interventions
This study will be a double blind, randomized cross-over trial with 2 interventions. Each subject will ingest two times 16 subsequent days either control supplements or supplements with added CRP on t
Sponsors
Wageningen University, Division of Human Nutrition
Eligibility
Inclusion criteria
Inclusion criteria: • Age: 18-40 year • BMI: 18.5-25 kg/m2 • Healthy: as judged by the participant • H2 producer (if they are part of the subsample of 20 subjects) • Having signed the informed consent form.
Exclusion criteria
Exclusion criteria: • Weight loss or weight gain of more than 5 kg during the last 2 months • Using an energy restricted diet during the last 2 months • Lack of appetite for any reason now or during the last 2 months • Restrained eater: for men >2.89 and for women >3.39, measured by the Dutch Eating Behaviour Questionaire • Smoking • Heavy alcohol use: >5 drinks/day • Pregnant or lactating women (current or the last 6 months) • Reported stomach or bowel diseases or disorders (e.g. irritable bowel syndrome) • Reported diabetes • Reported thyroid disease or any other endocrine disorder • Using medication other than birth control, paracetamol, acetylsalicylic acid (aspirin), hay fever, and asthma • Antibiotic use 5.8 mmol/l (if they are part of the subsample of 20 subjects) • Working at or doing an MSc. thesis at the Division of Human Nutrition of Wageningen University • Volunteers who participated in the Matrix study (NTR3601) • Subjects who (are planning to) participate in another scientific study during the period in which this nutritional study is performed
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary Objective: To study the effects of 2 week supplementation of 10g fibre out of CRP on energy intake in healthy subjects. | — |
Secondary
| Measure | Time frame |
|---|---|
| Our secondary objectives are to investigate whether these effects co-exist with changes in feelings of satiety, glucose, leptin, insulin responses, changes in fermentation activity and changes in immunological parameters (i.e. faecal parameters, and immunological parameters in blood) to explore underlying biological mechanisms. Glucose, leptin, insulin responses, changes in fermentation activity and changes in immunological parameters will only be determined in a subsample of the pupulation: n=20. | — |
Contacts
Public ContactAnne Wijlens
PO Box 8129
Outcome results
None listed