Natural killer cell receptor variability during the menstrual cycle

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON29470

Enrollment

Registered

2020-06-03

Start date

2020-04-01

Completion date

Unknown

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

None

Eligibility

Inclusion criteria

Inclusion criteria: Group 1: healthy women (no chronic medical conditions like chronic hypertension, chronic kidney failure, chronic immune conditions (SLE) or chronic medication use) with a regular natural menstrual cycle of 28 days (+/- 3 days), defined by no contraceptive use or healthy women with a copper spiral Group 2: healthy men (no chronic medical conditions, like chronic hypertension, chronic kidney failure, chronic immune conditions (SLE) or chronic medication use)

Exclusion criteria

Exclusion criteria: - Current or recent (<2 weeks) symptomatic infection - Previous pregnancy with complications, such as repeated miscarriages, preeclampsia, or diabetes gravidarum - Unable to give mentally capable consent in Dutch

Design outcomes

Primary

Measure	Time frame
Percentage of NK cells with activating and inhibitory receptors in peripheral blood	—

Secondary

Measure	Time frame
Percentage of NK cells with activating and inhibitory receptors in menstrual blood	—

Contacts

Public ContactDenise Habets

Maaastricht UMC+

denise.habets@mumc.nl0031433874152

Outcome results