labourpain
Conditions
Interventions
The following drugs are used in a patient controlled method:
1. Pethidine
2. Remifentanil
3. Fentanyl.
Medication will be started in active labour en will be continued untill complete dilation of the cervix is achieved.
Sponsors
Bronovo hospital,
Department of Obstetrics and Gynaecology, The Hague
Eligibility
Inclusion criteria
Inclusion criteria: 1. Age: at least 18 years old; 2. Between 37 and 42 weeks of gestation; 3. ASA physical status I or II.
Exclusion criteria
Exclusion criteria: 1. ASA physical status >= III; 2. Obesity (BMI equal or more than 40 kg/m2); 3. Substance abuse history; 4. High risk patients: including pre-eclampsia (diastolic pressure equal or more than 100, proteinuria), hepatic insufficiency or renal failure, severe asthma, poorly controlled diabetes mellitus); 5. Premature labour; 6. Drug allergy; history of hypersensitivity to opioid substances.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Quality of pain relief determined by Visual Analogue Scale, PCA demands/rewards and the number of parturients crossing over to epidural analgesia; 2. Patient satisfaction; 3. Fetal Outcome as determined by Apgar, NACS and requirement for naloxone; 4. Presence of opioid substances in umbilical and maternal blood samples. | — |
Contacts
Public ContactM.R. Douma
Leiden University Medical Center Department of Anesthesiology P.O. Box 9600
Outcome results
None listed