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Train the sedentary brain: move smart. The cognitive benefits of an interactive cycling training in APOEe4 carriers and non-carriers in early stage dementia

Train the sedentary brain: move smart. The cognitive benefits of an interactive cycling training in APOEe4 carriers and non-carriers in early stage dementia

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
NL-OMON
Registry ID
NL-OMON29449
Enrollment
171
Registered
2015-10-07
Start date
2015-09-01
Completion date
Unknown
Last updated
2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dementia, Alzheimer, Cognitive decline, Physical activity

Interventions

Within the study, three interventions are provided: (1) Interactive aerobic stationary cycle training, (2) Aerobic stationary cycle training, (3) Non-aerobic stretching and toning exercises. Forty-fi

Sponsors

Radboudumc
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Age > 60 years; diagnosis of dementia; Mini Mental State Examination score higher than 20; having insufficient physical activity according to the ACSM guideline for older adults, maximum of 30 minutes five days a week moderate intensity

Exclusion criteria

Exclusion criteria: Wheelchair bound, use of dementia targeted nutritional supplements (e.g. Souvenaird) within the last three months, severe cardiovascular problems that limit physical activity, brain trauma, epilepsy, progressive or terminal disease, severe depression, history of alcoholism, severe visual problems, severe auditory problems, problems with the Dutch language and mental incompetence

Design outcomes

Primary

MeasureTime frame
Executive functioning (set-shifting, response inhibition)

Secondary

MeasureTime frame
Verbal and visual-spatial memory, working memory, attention, psychomotor speed, physical fitness, levels of physical activity, quality of life. Frailty (Evaluative Frailty Index for Physical Activity)

Contacts

Public ContactEsther G.A. Karssemeijer

Radboud universitair medisch centrum - hp 925 | Postbus 9101

Esther.Karssemeijer@radboudumc.nlT (024) 36 16779

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)