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A simplified diagnostic algorithm for suspected pulmonary embolism

A simplified diagnostic algorithm for patients with clinically suspected acute pulmonary embolism

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
NL-OMON
Registry ID
NL-OMON29438
Enrollment
3260
Registered
2013-10-01
Start date
2013-10-07
Completion date
Unknown
Last updated
2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diagnostic algorithm / diagnostisch algoritme Pulmonary embolism / longembolie

Interventions

A prospective multi-center management registration of consecutive patients with suspected (recurrent) PE. Participants will be evaluated according to the YEARS algorithm consisting of three items of t
g/mL, and in patients with &#8805
1 items and a D-dimer level <0.5 &#956
g/mL a PE is excluded without CTPA. In the other patients a CTPA will be performed. All patients will be followed for a period of 3 months.

Sponsors

Leiden University Medical Center
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Consecutive patients with suspected (recurrent) PE.

Exclusion criteria

Exclusion criteria: -life expectancy <3 months - treatment with full-dose therapeutic low molecular weight heparin or unfractionated heparin that was initiated 24 hours or more prior to eligibility assessment - treatment with vitamin K antagonists (coumarin derivates) - contraindication to helical CT.

Design outcomes

Primary

MeasureTime frame
(recurrent) PE, DVT

Secondary

MeasureTime frame
mortality, number of performed CTPA.

Contacts

Public ContactTom Hulle, van der

Department of Thrombosis and Haemostasis Leiden University Medical Center Albinusdreef 2, P.O Box 9600

t.van_der_hulle@lumc.nl+ 31- 71-526-8132

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)