Long-term effects of bariatric surgery.

The long-term effects of bariatric surgery on metabolism, behavior and striatal dopamine receptors.

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON29394

Enrollment

Registered

2012-11-04

Start date

2012-12-01

Completion date

Unknown

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

obesity metabolic syndrome bariatric surgery dopamine receptors obesitas metabool syndroom bariatrische chirurgie dopamine receptoren

Interventions

None listed

Eligibility

Inclusion criteria

Inclusion criteria: Pre-menopausal Caucasian women that took part in our previous study "The pleiotropic effects of bariatric surgery" and underwent bariatric surgery > 1 year ago.

Exclusion criteria

Exclusion criteria: 1. Use of medication which interferes with dopamine metabolism; 2. Claustrophobia; 3. Pregnancy; 4. Tobacco use (i.e. smokers); 5. Unwilling or unable to provide informed consent.

Design outcomes

Primary

Measure	Time frame
Striatal dopamine D2/3 receptor availability.	—

Secondary

Measure	Time frame
1. Plasma levels of several hormones, metabolites and peptides involved in appetite regulation and glucose metabolism; 2. Behavioral parameters (measured via questionnaire and computer task).	—

Contacts

Public ContactE.M. Zwaal, van der

Academisch Medisch Centrum Afdeling Nucleaire Geneeskunde F2-232 Meibergdreef 9

e.m.vanderzwaal@amc.uva.nl

Outcome results