Mitral regurgitation
Conditions
Interventions
Cardiovascular magnetic resonance imaging (CMR) before MitraClip implantation and at 4 months after implantation.
Sponsors
University Medical Center Groningen
Eligibility
Inclusion criteria
Inclusion criteria: In order to be eligible to participate in this study, a subject must be scheduled for percutaneous mitral valve repair using the MitraClip.
Exclusion criteria
Exclusion criteria: Patients will be excluded from this study for any of the following reasons: - not eligible for percutaneous MitraClip implantation; - pregnancy or lactation; - contraindication for CMR imaging (known claustrophobia; tattoos containing metallic dyes; body mass >250 kg;, ferromagnetic objects in the body, e.g. non-MRI compatible pacemaker); - general condition which, according to the clinical judgment of the investigator and/or treating physician, does not allow the patient to participate in the study;. - patients with a high degree atrioventricular block will be excluded from adenosine administration.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in left ventricular end diastolic volume (EDV) and myocardial blood flow (MBF). | — |
Secondary
| Measure | Time frame |
|---|---|
| End systolic volume, left ventricular ejection fraction, stroke volume, regurgitant volume, mitral annulus diameter, left atrial size, left ventricular mass, wall strass, native T1, extracellular volume. | — |
Contacts
Public ContactP. van der Harst
Outcome results
None listed