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Difference in digestion and absorption of milk proteins

The digestion and absorption kinetics of micellar casein versus caseinate in healthy young men

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
NL-OMON
Registry ID
NL-OMON29333
Enrollment
45
Registered
2015-06-03
Start date
2015-09-01
Completion date
Unknown
Last updated
2024-06-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

protein digestion and absorption milk proteins whole-body protein synthesis eiwitvertering melkeiwitten eiwitsynthese

Interventions

each subject will participate in one trial, randomly assigned. Intervention consists of the ingestion of an intrinsically labeled protein supplement: micellar casein, calcium caseinate, or caseinate f

Sponsors

Maastricht University
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: - Males - Aged between 18-35 years - Healthy, recreationally active (participating in recreational sports activities ¡Ü 3 times per week) - BMI < 25 kg/m2 - No physical limitations (i.e. able to perform all activities associated with daily living in an independent manner).

Exclusion criteria

Exclusion criteria: - Female - Smoking - Allergies to milk proteins - Musculoskeletal disorders - Use of any medications known to affect protein metabolism (i.e. corticosteroids, non-steroidal anti-inflammatories, or prescribed acne medications). - Participation in any structured regular exercise program - Chronic use of gastric acid suppressing medication or anti-coagulants - Unstable weight over the last three months - Pathologies of the gastrointestinal tract

Design outcomes

Primary

MeasureTime frame
exogenous phenylalanine appearance rates

Secondary

MeasureTime frame
whole-body protein synthesis plasma insulin, glucose and amino acid concentrations

Contacts

Public ContactMilou Beelen

School of Nutrition and Translational Research in Metabolism (Nutrim)

E Milou.Beelen@maastrichtuniversity.nlT +31 (0)43 3881394

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)