Ventricular arrhythmias after LV reconstruction according to Dor. Kamer ritmestoornissen na LV reconstructie volgens Dor.
Conditions
Interventions
Endocardial encircling cryoablation (control) with additional epicardial cryoablation (study group) at the aneurysm scar borderzone with overlapping applications (up to -150C for 90s).
Sponsors
Departments of Cardiology and CardioThoracic Surgery
Leiden University Medical Center
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients referred for LV reconstruction according to Dor; 2. Spontaneous or inducible ventricular arrhythmias.
Exclusion criteria
Exclusion criteria: 1. Age <18 years; 2. Inability to comply with the protocol.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| >50ms conduction delay or conduction block between the aneurysm scar, encircled by cryoablation, and the healthy myocardium. Conduction properties are measured before and after cryoablation via temporary epicardial pacemaker leads between the aneurysm scar and the healthy LV and RV. All electrograms are stored on an electrophysiological recording system for off-line analysis. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Inducibility during post operative electrophysiological study of sustained monomorphic ventricular arrhythmias lasting >30s or requiring termination because of hemodynamic compromise; 2. Sustained ventricular arrhythmias recorded on ICD during follow-up. | — |
Contacts
Public ContactK. Zeppenfeld
LUMC Postbus 9600
Outcome results
None listed