Growth
Conditions
Interventions
Subjects will follow a regular diet for seven days followed by evaluation of blood pressure at our outpatient clinic. Several weeks later they use a regular diet enriched with 0,12 gram/kg/day salt (h
Sponsors
VU University Medical Center Amsterdam
Eligibility
Inclusion criteria
Inclusion criteria: Participants of the “Study Towards the Effect of Postdischarge nutrition on growth and body composition in infants born <32 weeks gestational age and/or <1500 gram birth weight” at 7 years of age.
Exclusion criteria
Exclusion criteria: Subjects with the following criteria will be excluded from the study: 1. Gastro-intestinal surgery and disease known to influence growth (i.e. cystic fibrosis); 2. Known presence of growth hormone, IGF-1, or other pituitary hormone deficiencies; 3. Concurrent therapies with substances known or suspected to be associated with alteration of growth; 4. Cardiac, renal, pulmonary, and liver disease; 5. Chromosomal and/or genetic syndromes (other than Silver-Russel); 6. Known presence of skeletal disease; 7. Severe illness.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Anthropometry; 2. Body composition (lean mass, fat mass). | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Blood pressure; 2. Endocrine parameters (e.g. insulin, glucose, IGF-1, FT4, TSH, cortisol); 3. Salt sensitivity of blood pressure; 4. Lipid status; 5. Neuromotor and cognitive development; 6. Bone mineralization. | — |
Contacts
Public ContactM. Lagemaat, van de
VU University Medical Center De Boelelaan 1117
Outcome results
None listed