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Treating trauma during a severely underweight state in anorexia nervosa patients, a multiple baseline case series study.

Treating trauma during a severely underweight state in anorexia nervosa patients, a multiple baseline case series study.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
NL-OMON
Registry ID
NL-OMON29188
Enrollment
10
Registered
2016-09-23
Start date
2016-11-01
Completion date
Unknown
Last updated
2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Trauma, PTSD, Anorexia, Eating Disorders, Severely underweight, Imagenary Rescripting, Intervention Study, Qualitative Research. Trauma, PTSS, Anorexia, Eetstoornissen, Ernstig ondergewicht, Imaginaire Rescripting, Interventie studie, Kwalitatief onderzoek.

Interventions

The IMRS treatment consists of 12 sessions of 90 minutes, and is conducted by either a health psychologist, psychotherapist, or clinical psychologist. The session frequency is twice a week. Imagery R
Arntz & Weertman 1999
Raabe et al., 2015
Smucker et al, 1995) which will be given in addition to the regular treatment that patients receive at Amarum. The investigational treatment focuses on changing the meaning of the memories of traumati

Sponsors

Psychiatric Hospital GGNet, Amarum University of Amsterdam Free University
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: - a BMI between 14 and 16.5 - current DSM IV diagnosis for anorexia nervosa or EDNOS - a PTSD diagnosis determined with the CAPS interview - age between 16 and 65 years old - an indication inpatient treatment

Exclusion criteria

Exclusion criteria: - estimated IQ < 80 - acute suicide risk - substance dependence - life threatening physical condition - start of new medication within 3 months before start of the study - ongoing trauma - medical history of psychosis, bipolar disorder, or borderline personality disorder

Design outcomes

Primary

MeasureTime frame
PTSD Symptom Scale-Self-rating (PSS-SR) is self-report questionnaire in which the DSM-IV symptoms for PTSD are addressed in 17 questions (Foa, Riggs, Dancu, & Rothbaum, 1993). The PSS-SR can be used either as a quantitative measure, to indicate the level of trauma-related complaints, or as a qualitative measure used to classify patients as suffering from PTSD yes or no. The PSS-SR will be collected weekly. VAS scales core emotional problems and beliefs The visual analog scale (VAS) is an instrument to measure subjective characteristics or attitudes. It is a psychometric response scale. The respondents may indicate on a line with two end points, to what extent they agree with an item. When the CAPS interview diagnosis a PTSD three personalized questions will be asked to personalize the VAS scales about negative thoughts about the self and the body. The VAS scales will be collected biweekly during the baseline period, after each IMRS session, biweekly during the follow up phase and once during the follow up measure. The following items are presented: 1)to what extent did you experience rage in the past three days 2)to what extent did you experience guilt in the past three days 3)to what extent did you experience shame in the past three days 4)to what extent did you experience disgust in the past three days 5)to what extent did you suffer from your “personalised negative thoughts about the self/ core belief” in the past three days 6)to what extent you suffer from your “personalised negative thoughts about the self/ core belief” in the past three days 7)to what extent you suffer from your “personalised negative thoughts about the body” in the past three days If supported by correlations, average values for negative emotions and for core beliefs will be used as primary outcomes, so that there are two dependent variables based on the set of VASs.

Secondary

MeasureTime frame
Secundary study parameters will be administered at several fixed timepoints Post-traumatic Cognitions Inventory (PTCI). The PTCI is a 36 item self-report questionnaire designed to measure trauma-related cognitions in three domains: negative cognitions about the world, negative cognitions about the self, and self-blame (Emmerik, Schoorl, Emmelkamp, & Kamphuis, 2006; Foa, Ehlers, Clark, Tolin, & Orsillo, 1999). BMI growth. BMI is a relative weight measure and is calculated as follows: body weight in kg /body height in m2. In the inpatient treatment, height is measured once during initial screening, and weight is measured minimal two times a week. We will ask patients for permission to use the height and weight information from their medical files. Eating Disorder Evaluation-Questionnaire (EDE-Q). The EDE-Q is a 36-item self-report questionnaire which measures core attitudinal features of the eating disorder, as well as the frequency of core eating disorder behavior over the previous 7 days. Difficulty with Emotion Regulation Scale (DERS). The DERS is a questionnaire which measures difficulties with emotion regulation, such as lacking emotional awareness, difficulty controlling impulses when distressed, and limited access to effective emotion regulation strategies. The DERS consists of 36 self-report items and can be used in nonclinical and clinical populations (Gratz & Roemer, 2004; Neumann, Van Lier, Gratz & Koot, 2010). Qualitative outcome measures • Therapist personal experiences and opinions on treating trauma during a severe underweight state (Therapist interview). We will conduct a semi-structured interview. • Patient’s personal experiences, treatment satisfaction, needs and opinions on treating trauma during a severe underweight state(Patient interview). We will conduct a semi-structured interview to assess the patient’s personal experiences and opinions about IMRS during their severely underweight state. • Collective therapists experiences and opinions

Contacts

Public ContactA. Arntz

Weesperplein 4

e-mail: A.R.Arntz@uva.nltelefoon: 020-5256728

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)