Kaolin, Celite, Heparin, Cardiopulmonary bypass, Cardiac surgery.
Conditions
Interventions
Group one: heparin management is guided by celite-ACT.
Group two: heparin management is guided by kaolin-ACT.
To measure the actual heparin concentration a duplicate HiTT (high dose thrombin time)
2. End cpb fibrinopeptide a (3mL)
3. Postoperative chest tube loss
4. Use of blood and bloodproducts
5. Length of stay in the ICU.
Sponsors
institutional
Eligibility
Inclusion criteria
Inclusion criteria: Patients presenting for coronary artery bypass grafting and/or valve repair/replacement.
Exclusion criteria
Exclusion criteria: Excluded are patients with heredetary coagulopathies, patients pre-operatively treated with unfractionated heparin, patients treated with aprotinin, and patients less than 18 years old.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Total heparin use at the end of CPB. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Fibrinopeptide A concentration; 2. Postoperative chest tube loss; 3. Use of blood and blood products; 4. Length of stay in the intensive care unit. | — |
Contacts
Public ContactA.J. Vries, de
University Medical Center Groningen (UMCG), Department of Anesthesiology, P.O. Box 30001
Outcome results
None listed