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VAgue Medical Problems In REsearch (VAMPIRE). Blood test ordering for unexplained complaints in general practice.

Blood test ordering for unexplained complaints in general practice.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
NL-OMON
Registry ID
NL-OMON29137
Enrollment
5000
Registered
2005-09-13
Start date
2002-01-01
Completion date
Unknown
Last updated
2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Unexplained complaints: those complaints in which the GP, after clarifying the reason for encounter, history taking and performing physical examination cannot establish a diagnosis.

Interventions

1. Immediate blood test ordering versus watchful waiting of 4 weeks with blood test ordering after four weeks only if complaints remain
2. Quality improvement strategy consisting of small group meetings, practice visits, patient leaflets and waiting room videotape versus no quality improvement strategy.

Sponsors

a. University of Maastricht, Care and Public Health Research Institute (CAPHRI), Department of General Practice. PO Box 616 6200 MD Maastricht The Netherlands b. Academic Medical Center - University of Amsterdam, Division of Clinical Methods & Public Health, Department of General Practice J3-370 PO Box 22660 1100 DD Amsterdam The Netherlands
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients of 18 years and above with unexplained fatigue; 2. Abdominal complaints; 3. Musculoskeletal complaints; 4. Weight changes or itching who have not contacted their GPs for the last six months with the same complaints and are able to speak, read and write Dutch.

Exclusion criteria

Exclusion criteria: The GP is worried that the patient has got serious pathology that makes watchful waiting unacceptable.

Design outcomes

Primary

MeasureTime frame
1. Accuracy of blood tests for serious pathology (per test and in combinations relevant for general practice), related and in addition to signs and symptoms, at the moment of presentation and after postponing test ordering for four weeks; 2. Adherence of GPs to instruction either to order blood tests directly or after a watchful waiting policy of four weeks.

Secondary

MeasureTime frame
1. Incidence of unexplained complaints in general practice; 2. Predictive value of GPs working hypothesis; 3. Duration of unexplained complaints; 4. Effect of unexplained complaints on quality of life of patients; 5. Effect of direct testing or watchful waiting on satisfaction with care, anxiety, medical consumption and absence from work of patients; 6. Effect of direct testing or watchful waiting on satisfaction, anxiety and insecurity of GPs; 7. Effect of quality improvement intervention on knowledge about the value of blood test ordering in unexplained complaints, communication skills and attitudes of GPs; 8. Barriers to and facilitators of proposing a watchful waiting strategy by GPs; 9. Costs of the quality improvement intervention.

Contacts

Public ContactG.J. Dinant

University Maastricht (UM), Department of General Practice, P.O. Box 616

geertjan.dinant@hag.unimaas.nl+31 (0)43 3882396

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)