dental caries radioiodine treatment (I131) differentiated thyroid carcinoma (DTC) salivary glands
Conditions
Interventions
Observational study.
Carious lesions will be scored from the dental record.
The patient visits the outpatient clinic once for a study visit. During this visit, the patient completes questionnaires,
Sponsors
T.P. Links, University Medical Center Groningen
Eligibility
Inclusion criteria
Inclusion criteria: - age at time of the first I131 treatment is at least 26 years - the patient is diagnosed with DTC at least 4 years ago - the patient has been treated with I131 - the patient visits a dentist and is dentate at the time of I131 treatment - the subject gives written informed consent for study participation
Exclusion criteria
Exclusion criteria: - history of Sjögren’s syndrome or other salivary gland disease affecting salivary gland function - the patient switched dentist in the period of 4 years before and 4 years after the first radioiodine therapy, with no (complete) transfer of the dental record. - the patient didn’t visit his/her dentist in the in the period of 4 years before and 4 years after radioiodine therapy. - the patient is mentally incapacitated
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incident dental caries lesions, extracted from the dental record (includes number of caries restorations, tooth extractions and documented carious lesions) | — |
Secondary
| Measure | Time frame |
|---|---|
| - Cumulative I131 dose - Number of I131 therapies - Xerostomia and oral hygiene questionnaire scores - Unstimulated and chewing stimulated whole saliva flow rates and pH - Site of carious lesions - Dutch Periodontal Screening Index (DPSI) score. | — |
Contacts
Public ContactT.P. Links
Hanzeplein 1
Outcome results
None listed