negative emotions fetal programming cognitive behaviour therapy pregnancy outcome negatieve emoties (angst en depressie) prenatale programmering cognitieve gedragstherapie zwangerschapsuitkomst
Conditions
Interventions
The cognitive behavioral therapy consists of 10-14 individual sessions, 6-10 sessions during pregnancy and 4-8 sessions after delivery (once a week). The CBT will be conducted by registered psychologi
Sponsors
University Medical Center Groningen
Eligibility
Inclusion criteria
Inclusion criteria: Having at least moderate depression and/or anxiety symptoms during pregnancy.
Exclusion criteria
Exclusion criteria: Women fulfilling one or more of the following criteria will be excluded from participation: 1. Multiparae pregnant women. We decided to exclude multiparae pregnant women as they have a markedly increased obstetric risk; inclusion will threaten the homogeneity of the study population and thereby decrease the sensitivity to detect effects; 2. High suicidal risk according to the suicidality subscale score on the MINI (defined as a positive response on the question on concrete suicide plans); 3. Presently receiving psychotherapy at a higher than twice a month rate; 4. Substantial physical disease or illegal substance abuse.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Behavioral/emotional problems at age 1.5 as assessed by the total problems scale of the Child Behavior Check List 1.5 – 5 years. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Mental, psychomotor and behavioral development of the child at age 18 months according to the Bayley scales; 2. Maternal anxiety and depression during pregnancy and 6 weeks postnatal; 3. Maternal attachment style; 4. Neonatal outcomes: birth weight, gestational age and Apgar score; 5. Health care consumption and general health status (economic evaluation). | — |
Contacts
Public ContactJ.L. Meijer
Hanzeplein 1
Outcome results
None listed