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PROBEL; Prognostics in the Treatment Evaluation of the National System for Veterans' Care

PROBEL; Prospective Observational Cohort study into the Predictors of Treatment Outcome for Veterans with full and subthreshold Posttraumatic Stress Disorder

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
NL-OMON
Registry ID
NL-OMON29049
Enrollment
260
Registered
2019-12-02
Start date
2020-02-01
Completion date
Unknown
Last updated
2024-06-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Posttraumatische Stressstoornis, Posttraumatic Stress Disorder

Interventions

This is an observational study with a naturalistic design. Treatment will be provided according to standard clinical care. At the five participating centers patients will receive conventional evidence

Sponsors

Stichting Centrum '45 partner in ARQ National Psychotrauma Center, Diemen/Oegstgeest, the Netherlands
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Soldiers and veterans who participated in a military deployment, who meet the diagnostic DSM-5 criteria for PTSD or subthreshold PTSD. Further inclusion criteria are age between 18 and 65 years and having a treatment indication for trauma-focused psychotherapy.

Exclusion criteria

Exclusion criteria: Acute suicidality and severe psychiatric co-morbidity that would impede undergoing trauma-focused therapy.

Design outcomes

Primary

MeasureTime frame
The primary outcome measure is change in PTSD symptom severity during the first year of treatment. We will develop a prognostic model that predicts treatment outcome based on PD (such as, stigma, shame, and guilt), NP (executive functions and verbal memory), and PP (the stress- and immune system) factors collected before starting and after a year of treatment.

Secondary

MeasureTime frame
The secondary outcome measures are change during the first year of treatment in depressive symptoms severity and level of daily functioning.

Contacts

Public ContactJorinde Gerrmann

Stichting Centrum '45 partner in ARQ National Psychotrauma Center

j.gerrmann@centrum45.nl+3120 627 4974

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)