breath analysis
Conditions
Interventions
Aeonose-based signatures of exhaled breath will be obtained from patients with suspected BC and a control group, paralleled by phenotyping of the BC patients according to the gold standard.
Sponsors
Alexander Monro Hospital, Bilthoven
Medisch Spectrum Twente, Enschede
Ziekenhuis Bernhoven, Uden
Eligibility
Inclusion criteria
Inclusion criteria: • Patients entering the hospital with suspected BC • Patients age of 18 years and older • Signed informed consent
Exclusion criteria
Exclusion criteria: Patients with a history of proven primary BC and other malignancies, • Patients currently treated with radio- or chemotherapy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary parameters of diagnostic relevance will be sensitivity, specificity, positive and negative likelihood ratio, and positive and negative predicted value of the Aeonose. Histopathological examination of the biopsies is considered the gold standard. | — |
Secondary
| Measure | Time frame |
|---|---|
| Patients Reported Outcome measures Cost-effectiveness analysis (Markov model) | — |
Contacts
Public ContactAnja Timmer-Bonte
Outcome results
None listed