End stage renal disease
Conditions
Interventions
• Katz ADL-6
• Lawton iADL
• Hand grip strength
• Fall risk
• Montreal Cognitive Assessment (MOCA)
• Letter Digit Substraction Test (LDST)
• 6-item Cognitive Impairment Test (6CIT)
• Geriatric Depres
GDS-15 if positive)
• Optimism check
• Surprise question
• Clinical Frailty Score
• Charlson co-morbidity index
• Mini Nutritional Assessment (MNA)
• EQ5D-5L
• iMTA Costs
• Short Form-12 (SF-12)
• Di
Sponsors
Leids Universitair Medisch Centrum
Eligibility
Inclusion criteria
Inclusion criteria: 1. Age > 65 years 2. eGFR 10-20 ml/min/1.73m2 (at least during 1 measurement in 3 months before inclusion)
Exclusion criteria
Exclusion criteria: - Unwilling or unable to provide (written) informed consent - Illiterate - If a patient appears to be severely cognitive impaired after evaluation of the cognitive function, the patient will be consulted by a geriatrician for further clinical evaluation, such as the presence of dementia. In case of diagnosis of cognitive impairment, the geriatrician will judge if patient is mental competent (“wilsbekwaam”) to provide informed consent to partici-pate in the study. If not, the patient will not be prospectively followed and no blood sample will be collected.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| QoL measured with CKD-PROMs (consisting of SF-12 and Dialysis Symptom Index) | — |
Secondary
| Measure | Time frame |
|---|---|
| Clinical outcomes (independent functionality, hospitalisation, mortality), cost-effectiveness and decisional regret | — |
Contacts
Public ContactMarjolijn van Buren
LUMC
Outcome results
None listed