Vasovagal syncope
Conditions
Interventions
1. Physical Counterpressure Manoeuvres
2. Midodrine.
Sponsors
Academic Medical Center
Eligibility
Inclusion criteria
Inclusion criteria: 1. Clinical diagnosis of classical neurally- mediated reflex syncope, based on the medical history ór non-classical diagnosis of neurally-mediated reflex syncope and a positive tilt-table test; 2. 3 syncope episodes in the last 2 years; 3. Recognizable prodromal symptoms; 4. Age 18-70 years.
Exclusion criteria
Exclusion criteria: 1. Suspected or certain heart disease and high likelihood of cardiac syncope; 2. Orthostatic hypotension; 3. Episodes of loss of consciousness different from syncope (e.g. epilepsy, psychiatric, metabolic, drop-attack, TIA, intoxication, cataplexy); 4. Steal syndrome; 5. Psychologically or physically (due to any other illness) or cognitively unfit for participation in the study according to the opinion of the investigator; 6. Patient compliance doubtful; 7. Patient geographically or otherwise inaccessible for follow-up; 8. Patient unwilling or unable to give informed consent; 9. Pregnancy; 10. Life expectancy < 1 year.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Total burden of syncope recurrence. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Time to first recurrence syncope and presyncope; 2. Presyncope burden; 3. Quality of life. | — |
Contacts
Public ContactW. Wieling
Academic Medical Center (AMC), Department of Internal Medicine, P.O. Box 22660
Outcome results
None listed