single neuron epilepsy seizures temporal lobe neural networks functional connectivity graph theory memory attention
Conditions
Interventions
None listed
Sponsors
Prof. Dr J.J. Heimans, neurologist, head of the Department of Neurology
VU University Medical Centre
PO Box 7057
1007 MB Amsterdam
The Netherlands
T +31 20 4442821
F +31 20 4442800
Email: JJ.Heimans@vumc.nl
Eligibility
Inclusion criteria
Inclusion criteria: Epilepsy patients with macroelectrode and microwire implants. No specific inclusion criteria for the study population apply additional to the standard clinical criteria for the indication of depth macroelectrodes, other than written informed consent.
Exclusion criteria
Exclusion criteria: Patients with a history of hypertension, or patients who are using anti-hypertensive medication at time of evaluation for this study, will be excluded from this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The main study parameters are the macro- and microelectrode recordings, assessing functional connectivity (SL and PLI) and neuronal brain networks (cluster coefficient and path length), seizure frequency and epilepsy burden. | — |
Secondary
| Measure | Time frame |
|---|---|
| These includes test results of the patients memory and attention tests. | — |
Contacts
Public ContactE. Dellen, van
Postbus 7057
Outcome results
None listed