asthma, COPD, diagnostic accuracy, STARD, intention to diagnose astma, COPD, diagnostische waarde, STARD, verdenking diagnose
Conditions
Interventions
Electronic nose: The Cyranose 320 (Smith Detections, Pasadena, Ca, USA), a handheld portable chemical vapor analyzer, containing a nanocomposite sensor array with 32 polymer sensors. Patients will bre
Sponsors
Academic Medical Centre Amsterdam
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients (>16 years old) getting a diagnostic work-up for asthma or COPD in the Academic Medical Centre (Amsterdam) will be included in the study; 2. Differential diagnosis of asthma, COPD, obstructive lung disease; 3. Clinical evaluation for reversibility (FEV1), airway hyperresponsiveness, airway obstruction.
Exclusion criteria
Exclusion criteria: Known current diagnosis of asthma and/or COPD.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcome parameter is the breathprint provided by the electronic nose. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. FEV1; 2. Reversibility in FEV1; 3. PC20 airway hyperresponsiveness; 4. Respiratory symptoms. | — |
Contacts
Public ContactNiki Fens
Clinical Research Fellow 'Electronic Nose' Academic Medical Center (AMC) University of Amsterdam Department of Pulmonology F5-260 P.O.Box 22660
Outcome results
None listed