Predictive value of nailfold Capillaroscopy and Antinuclear antibodies in children with RaYnaud’s phenomenon

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON28940

Enrollment

Registered

2018-10-09

Start date

2019-03-01

Completion date

Unknown

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Raynaud's phenomenon

Interventions

None

Eligibility

Inclusion criteria

Inclusion criteria: - Diagnoses of Raynaud's phenomenon - Underwent NCM when they were under 18 years of age - Currently 16 years of age or older

Exclusion criteria

Exclusion criteria: None

Design outcomes

Primary

Measure	Time frame
The primary objective of the study is to determine the sensitivity and specificity of NCM in combination with ANA for predicting an underlying CTD in children with Raynaud's.	—

Secondary

Measure	Time frame
- To study the changes of the nailfold capillaroscopic pattern over time (>5 years): pattern, number of capillaries, number of giant capillaries, hemorrhages - To describe the characteristics of our cohort of children/young adults with Raynaud’s phenomenon with a follow-up of >5 years - To study the predictive value of symptoms specific for CTD and abnormal lab tests (CRP, BSE, kidney function, complement C3 and C4, erythrocyteuria, cryoglobulinemia)	—

Measure

Time frame

- To study the changes of the nailfold capillaroscopic pattern over time (>5 years): pattern, number of capillaries, number of giant capillaries, hemorrhages - To describe the characteristics of our cohort of children/young adults with Raynaud’s phenomenon with a follow-up of >5 years - To study the predictive value of symptoms specific for CTD and abnormal lab tests (CRP, BSE, kidney function, complement C3 and C4, erythrocyteuria, cryoglobulinemia)

—

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)