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PRACTISE: Promoting acute thrombolysis for ischemic stroke.

A cluster randomized controlled trial to assess the effect of implementation strategies on the rate and effects of thrombolysis for acute ischemic stroke.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
NL-OMON
Registry ID
NL-OMON28863
Enrollment
7000
Registered
2005-09-22
Start date
2005-10-01
Completion date
Unknown
Last updated
2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Stroke

Interventions

The high intensity intervention consists of the introductionof a set of implementation tools, directed at the four levels where barriers against trombolysis are expected. This toolkit will be explaine

Sponsors

Erasmus MC Rotterdam
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All patients who are admitted with acute stroke, i.e. patients with an acute focal neurological deficit, which cannot be explained by a condition other than stroke, andonset of symptoms not longer than 24 hours ago, will be included in the trial. Thesepatients will be registered, and a minimal set of baseline data will be recorded. Patients with acute stroke, who are admitted within 4 hours from onset of symptoms will be registered and followed up after three months.

Exclusion criteria

Exclusion criteria: Age under 18.

Design outcomes

Primary

MeasureTime frame
Treatment with thrombolysis or not in all registered patients.

Secondary

MeasureTime frame
Admission within 3 hours after onset of symptoms,death or disability at three months (in the subgroup of patients withischemic stroke who were admitted within 3 hours).

Contacts

Public ContactMaaike Dirks

Erasmus Medical Center, Department of Neurology, Suite Ee 2240, P.O. Box 1738

m.dirks@erasmusmc.nl

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)