oropharyngeal cancer
Conditions
Interventions
None listed
Sponsors
Erasmus MC
Eligibility
Inclusion criteria
Inclusion criteria: In order to be eligible to participate in this study, a subject must meet all of the following criteria: - Patients with histologic proven cT1-2N1-3M0 or cT3-4N0-3M0 p16 negative stage III - IVb p16 negative or stage I-III p16 positive squamous cell carcinoma of the oropharynx - 18 years or older. - A history of smoking - Scheduled for primary chemo-radiotherapy with cisplatin where a MRI scan is part of the standard radiotherapy work up - Included in the BIO-ROC study and for whom the biopsy was successfully obtained. - Written informed consent.
Exclusion criteria
Exclusion criteria: A potential subject who meets any of the following criteria will be excluded from participation in this study: - Patients with recurrence of previously confirmed head and neck squamous cell carcinoma. - Patients with other types of malignancies in the head and neck region - Having any physical or mental status that interferes with the informed consent procedure or study procedures. - Contraindications for MRI (e.g. claustrophobia, arterial clips in central nervous system)
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| local regional response 3 months after treatment | — |
Primary
| Measure | Time frame |
|---|---|
| local regional control (LRC) 2 years after treatment | — |
Contacts
Public ContactSteven Petit
Erasmus MC Cancer Institute
Outcome results
None listed