Breast cancer, Axillary lymph node dissection, Breast cancer related lymphedema, Axillary reverse mapping
Conditions
Interventions
A standard ALND compared with a limited and more tailor-made axillary lymph node dissecion, based on the ARM technique.
Sponsors
none
Eligibility
Inclusion criteria
Inclusion criteria: Female patient aged 18 years and over presenting in one of the participating hospitals with the diagnosis invasive breast cancer and an indication for a complementary ALND based on a positive SLN are eligible for an ALND-ARM procedure. The indication for a complementary ALND will be made in a multidisciplinary team including an oncologic surgeon, medical oncologist, pathologist, radiologist and a radiotherapist.
Exclusion criteria
Exclusion criteria: Primary ALND based on a clinical positive axilla, a contra-indication for SLNB, a history of (breast) cancer, an adverse event during the previous SLNB and pregnancy will be excluded from participation of the RCT.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Lymphedema of the upper extrimity. | — |
Secondary
| Measure | Time frame |
|---|---|
| The secondary outcome measurements include other postoperative complications (pain, paresthesia, numbness and loss of shoulder mobility), quality of live and axillary recurrence ratio. | — |
Contacts
Public ContactPaul D. Gobardhan
Department of Surgery Amphia hospital Breda
Outcome results
None listed