Treatment of skin severity in Ichthyosis with hyperbaric oxygen therapy

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON28824

Enrollment

Registered

2019-09-03

Start date

2021-02-01

Completion date

Unknown

Last updated

2025-03-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ichtyosis, bacterial skin infection, fungal skin infection

Interventions

Hyperbaric oxygen therapy

Eligibility

Inclusion criteria

Inclusion criteria: Confirmed diagnosis of ichtyosis, >18 years old, can understand Dutch or English language

Exclusion criteria

Exclusion criteria: Unfit for hyperbaric oxygen therapy (as determined by hyperbaric physician), unable to give informed consent, language barrier, actively smoking or stopped smoking <3 months ago

Design outcomes

Primary

Measure	Time frame
Feasability of the intervention in this patient group; changes in PROMs (Patients Global Assessment, pain, desquamation, sleep and pruritus scores, medication usage and Quality of life using skindex-29); changes in doctors reported outcomes (objective skin scoring with IGA-NS, TLSS NS and BSA); assessing the safety and feasibility of HBO in patients with ichthyosis	—

Secondary

Measure	Time frame
Changes in laboratory findings; Changes in histologic findings in skin biopsies reviewed by a pathologist; Side effects; Regret analysis	—

Contacts

Public ContactRutger Lalieu

Amsterdam University Medical Center

r.c.lalieu@amsterdamumc.nl+31654347959

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)