Identifying patients with hereditary and familial colorectal cancer by using an online risk tool

Identifying the risk of hereditary and familial colorectal cancer in colorectal cancer patients by using an online risk tool: An evaluation based on a stepped wedge design

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON28822

Enrollment

104

Registered

2015-08-13

Start date

2015-02-01

Completion date

Unknown

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

colorectal cancer, questionnaire, heredity, Lynch syndrome, familial colorectal cancer, family history

Interventions

Intervention: offering an online risk assessment questionnaire to CRC patients, to facilitate the detection of CRC patients with hereditary or familial CRC Control: Hospital-based standard practice f

Eligibility

Inclusion criteria

Inclusion criteria: Patients with a diagnosis of CRC who have a first appointment at the outpatient clinic (before treatment has started). If a patient undergoes surgery before going to an outpatient clinic (in case of an acute surgery indication), this patient will not be included in our study

Exclusion criteria

Exclusion criteria: Patients who have received a CRC treatment before their intake visit will be excluded

Design outcomes

Primary

Measure	Time frame
Percentage of all included patients who receive a recommendation for regular surveillance colonoscopies for himself/herself and/or relatives, provided by a clinical geneticist.	—

Secondary

Measure	Time frame
-Percentage of all included patients with a referral to a clinical geneticist -Percentage of referred patients fulfilling referral criteria for a Lynch syndrome suspicion -Percentage of all included patients with genetically confirmed Lynch syndrome -Percentage of all included patients with confirmed other hereditary CRC syndromes (such as polyposis syndromes) -Percentage of referred patients fulfilling FCC criteria -Percentage of all included patients who receive a surveillance advice per time period (month or season) -Percentage of referred patients not fulfilling referral criteria for FCC, a Lynch syndrome suspicion or other hereditary CRC syndromes -All the above mentioned outcome measures per hospital -Percentage of patients not adhering to referral advice -The number of changes in family history after verification of the completed questionnaire at the outpatient clinic -Reasons for not filling out the questionnaire at home or at all -Usability of the questionnaire for health care providers and patients	—

Measure

Time frame

-Percentage of all included patients with a referral to a clinical geneticist -Percentage of referred patients fulfilling referral criteria for a Lynch syndrome suspicion -Percentage of all included patients with genetically confirmed Lynch syndrome -Percentage of all included patients with confirmed other hereditary CRC syndromes (such as polyposis syndromes) -Percentage of referred patients fulfilling FCC criteria -Percentage of all included patients who receive a surveillance advice per time period (month or season) -Percentage of referred patients not fulfilling referral criteria for FCC, a Lynch syndrome suspicion or other hereditary CRC syndromes -All the above mentioned outcome measures per hospital -Percentage of patients not adhering to referral advice -The number of changes in family history after verification of the completed questionnaire at the outpatient clinic -Reasons for not filling out the questionnaire at home or at all -Usability of the questionnaire for health care providers and patients

—

Contacts

Public ContactE. Dekker

Meibergdreef 9

e.dekker@amc.uva.nl+31 (0)20 5664702

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)