traumatic stress
Conditions
Interventions
Socially-evaluated cold pressor task versus warm water control condition without social evaluation. Additionally, all participants will watch a trauma film, known to induce intrusive memories in the
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Sponsors
Academic Medical Center
Eligibility
Inclusion criteria
Inclusion criteria: Male sex; - Age 18-40 years; - Caucasian ethnic background; - Body Mass Index (BMI) between 18.5 and 30; - Fluent in Dutch language (oral and written); - In possession of a smartphone (IOS or Android system), because of smartphone application used for intrusion diary .
Exclusion criteria
Exclusion criteria: - Current major medical disorder; - Current use of medications known to impact ANS and HPA axis function; - Lifetime psychiatric diagnosis; - Current significant anxiety or depressive symptoms, as objectified with the DASS-21; - Current significant PTSD symptoms, as objectified with the PCL-5; - Previous exposure to the traumatic events portrayed in the film; - Current habitual smoking.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Differences between stressor and control condition in: salivary cortisol and alpha amylase output as measured six times during the experimental paradigm and the total frequency of intrusive memories during the 7 days following the experimental paradigm. | — |
Secondary
| Measure | Time frame |
|---|---|
| - Differences between stressor and control condition in accuracy of voluntary memory and characteristics of intrusive memories related to the trauma film. - Associations between baseline glucocorticoid receptor functioning, cortisol and alpha amylase stress reactivity during the experimental paradigm and voluntary memory accuracy and intrusive memory frequency and characteristics. | — |
Contacts
Public ContactMirjam Zuiden, van
Meibergdreef 5
Outcome results
None listed