drug-drug interactions, clinical decision support systems, intensive care, medication safety
Conditions
Interventions
A clinical decision support system will be implemented that produces alerts to warn for DDIs that are clinically relevant for the ICU setting. Participating ICUs will receive a training for use of the
Sponsors
Amsterdam UMC locatie AMC (AMC-UvA)
Eligibility
Inclusion criteria
Inclusion criteria: partcipating ICUs: Dutch Intensive Care Units using Metavision as a patient data management system.
Exclusion criteria
Exclusion criteria: Patients: patients admitted to one of the participating ICUs under the age of 18 will be excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in the incidence of clinically relevant potential drug-drug interactions per 1000 medication administrations | — |
Secondary
| Measure | Time frame |
|---|---|
| - The number of (clinically relevant) potential drug-drug interactions per patient - The proportion of patients admitted to the ICU with at least one (clinically relevant) potential drug-drug interactions - ICU length of stay - The override rate of (clinically relevant) potential drug- drug interaction alerts - The number of ADEs related to drug-drug interactions per 1000 medication administrations - The proportion of appropriately handled clinically relevant potential drug-drug interactions | — |
Outcome results
None listed