colorectal cancer, serrated polyposis syndrome
Conditions
Interventions
Data are collected in prospective manner from patients during routine surveillance endoscopies with removal of all polyps > 3 mm and/or with a adenomatous aspect.
Sponsors
Academic medical centre, Amsterdam
Eligibility
Inclusion criteria
Inclusion criteria: HPS patients defined as: > 5 HPs/SSA proximal to the sigmoid, of which 2 > 10 mm in diameter, or more than 20 HPs/SSAs distributed throughout the colon.
Exclusion criteria
Exclusion criteria: Carriers of a germline mutation in the MutYH or APC gene and individuals who have undergone a total colonic resection.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| - Incidence of interval colorectal cancer during protocolled endoscopic surveillance of SPS patients | — |
Secondary
| Measure | Time frame |
|---|---|
| - Incidence and characteristics of polyps found during endoscopic surveillance of SPS patients - The ratio of annual and biennial surveillance advise - Incidence of conversion to preventive colorectal surgery - Incidence of post-colonoscopy complications | — |
Contacts
Public ContactJ.E.G. IJspeert
Academic Medical Center Amsterdam
Outcome results
None listed