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ProMuscle in Practice: Effectiveness of a combined resistance exercise and nutrition intervention to promote maintenance of physical functioning of community-dwelling elderly in a real-life setting

ProMuscle in Practice: Effectiveness of a combined resistance exercise and nutrition intervention to promote maintenance of physical functioning of community-dwelling elderly in a real-life setting

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
NL-OMON
Registry ID
NL-OMON28702
Enrollment
200
Registered
2016-08-30
Start date
2016-09-05
Completion date
Unknown
Last updated
2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Physical functioning, community-dwelling older adults Fysiek functioneren, thuiswonende ouderen

Interventions

The intervention subjects will receive a 12 week intensive intervention and a 12 week maintenance period. The intensive intervention consists of: 1) Twice weekly1-hour progressive resistance-type exe

Sponsors

Wageningen UR Food & Biobased Research
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: - Aged 65 years or over - Living independently in one of the five selected municipalities - Able to understand Dutch language - Pre-frail or frail according to Fried criteria - Having signed informed consent - Additional for those not recruited via care organisation: reported loss of muscle strength

Exclusion criteria

Exclusion criteria: - Having an allergy for or being sensitive to milk proteins - Being lactose intolerant - Having diagnosed COPD or cancer - Suffering from diabetes type 1 or type II that is unstable, not well regulated with medication, or not being able to notice when they get hypoglycaemia - Suffering from hypertension (systolic blood pressure >160 mmHG) that is not well regulated with medication - Suffering from severe heart failure - Suffering from with renal insufficiency (eGFR < 60 ml/min ) - Having physical impairment that unable them to participate in the exercise training - Having cognitive impairments that unable them to understand and complete questionnaires - Receiving terminal care - Having a newly placed artificial hip or prosthesis, unless fully recovered - Having had recent surgery (< 3 months) in whom the exercises might stress the surgery scars

Design outcomes

Primary

MeasureTime frame
The primary outcome of this study is the change in physical functioning (Short Physical Performance Battery score).

Secondary

MeasureTime frame
Secondary parameters are measured at 12, 24 and 26 weeks: Quality of life (EQ-5D-5L), physical functioning (Timed Up-and-Go, 6 minute walking test), leg muscle strength (3-RM and dynamometer), body composition (DEXA), protein intake (3-day food diaries), social participation, Activities of Daily Living (ADL) and behavioural determinants. Besides, healthcare and patient costs and indicators related to process evaluation (acceptability, applicability, integrity, reach/dose) are secondary outcomes.

Contacts

Public ContactEsmée Doets

Bornse Weilanden 9

esmee.doets@wur.nl0317-480262

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)