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Effect of ingestion of mate tea and chocolate in the endothelium of individuals with HIV / AIDS.

Effect of ingestion of mate tea and chocolate in the endothelium of individuals with HIV / AIDS: A randomized, blinded, placebo-controlled trial.

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
NL-OMON
Registry ID
NL-OMON28657
Enrollment
180
Registered
2011-12-05
Start date
2011-05-05
Completion date
Unknown
Last updated
2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

HIV and HAART. Key words: Endothelium, HIV / AIDS, Antiretroviral Therapy High Power, cocoa, tea, mate. Endotheel, HIV / AIDS, antiretrovirale therapie High Power, cacao, thee, mate.

Interventions

Individuals are supplemented with 65g chocolate bars containing cocoa 36g and 300 mL of mate tea. As placebo tablets were formulated without cocoa and 300 mL of prepared liquid with similar appearance

Sponsors

University of Sao Paulo - School of Public Health - Brazil
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Individuals of both sexes aged 19 to 59 years with HIV / AIDS and who were on regular treatment with HAART for at least six months.

Exclusion criteria

Exclusion criteria: Individuals who had at least one of the following criteria: History of myocardial infarction or stroke, cardiac arrhythmia, Chagas disease, heart failure, in lipid-lowering medication use, weight greater than 150kg, diabetes mellitus, hypertension, renal disease (creatinine> 2.0 mg / dL), severe intestinal disease that prevents the use of diet, hypothyroidism (TSH> 6.0 IU / mL), liver failure, malignant neoplasm, active opportunistic infection at the time, pregnancy, chronic alcoholism, vegetarian diet ; other individuals participating in research, and supplements or intolerance to any of its components.

Design outcomes

Primary

MeasureTime frame
Assessing the impact of eating chocolate and mate tea on endothelial function and vascular elasticity of patients with HIV / AIDS.

Secondary

MeasureTime frame
1. Assessing the impact of supplementation with cocoa and mate tea in inflammatory parameters; 2. Assessing the impact of supplementation with cocoa and mate tea in the biochemical parameters including lipid profile; 3. To evaluate anthropometric measurements before and after intervention.

Contacts

Public ContactLiania Alves Luzia
lianialuzia@usp.br55 11 30617867

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)