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To improve early recgonition and tailored treatment of behavioral changes in patients with Alzheimer's disease and Mild Cognitive Impairment visiting the memory clinic

BEhavioural symptoms in Alzheimer’s disease Towards early identification and Treatment: the BEAT-IT study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
NL-OMON
Registry ID
NL-OMON28628
Enrollment
150
Registered
2018-09-06
Start date
2018-10-01
Completion date
Unknown
Last updated
2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Alzheimer's disease, Mild Cognitive Impairment, dementia De ziekte van Alzheimer, Milde Cognitieve Stoornissen, dementie

Interventions

In the first part of the study, a historical control group will be recruited that will receive care as usual. After one year, we will enroll a second cohort of participants that will receive a struc

Sponsors

Erasmus Medical Center
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: - Clinical diagnosis of Alzheimer's disease or Mild Cognitive Impairment. Based on patient history, neuropsycholoigcal assessment, and neuro-imaging - Presence of neuropsychiatric symptoms (score >1 on NPI-Q) - Mini-Mental State Examination score > 15 - Patients need to live at their home and be outpatient - Until 2 years after diagnosis - Reliable informant needs to be available

Exclusion criteria

Exclusion criteria: - Legally incapable and unable to give written consent to particpate - Severe (premorbid) psychiatric disorders such as schizophrenia or bipolar disorder, or current abuse of alcohol or drugs - Evidence of current delirium or previous delirium in the past six months - Patients meet criteria for dementia with Lewy bodies, behavioral variant of Frontotemporal Dementia, or vascular dementia - Currently participating in a clinical trial

Design outcomes

Primary

MeasureTime frame
Quality of life of patient and their caregiver

Secondary

MeasureTime frame
- Neuropsychiatric symptoms - Caregiver burden - Confidence mangaging neuropsychiatric symptoms - Psychotropic drug use - Cost-effectiveness - Feasibility of the intervention will be examined by the use of semi-structured interviews with a part of the patients and carergivers that underwent the intervention.

Contacts

Public ContactWillem Eikelboom
w.eikelboom@erasmusmc.nl010-7034793

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)