Alzheimer's disease, Mild Cognitive Impairment, dementia De ziekte van Alzheimer, Milde Cognitieve Stoornissen, dementie
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: - Clinical diagnosis of Alzheimer's disease or Mild Cognitive Impairment. Based on patient history, neuropsycholoigcal assessment, and neuro-imaging - Presence of neuropsychiatric symptoms (score >1 on NPI-Q) - Mini-Mental State Examination score > 15 - Patients need to live at their home and be outpatient - Until 2 years after diagnosis - Reliable informant needs to be available
Exclusion criteria
Exclusion criteria: - Legally incapable and unable to give written consent to particpate - Severe (premorbid) psychiatric disorders such as schizophrenia or bipolar disorder, or current abuse of alcohol or drugs - Evidence of current delirium or previous delirium in the past six months - Patients meet criteria for dementia with Lewy bodies, behavioral variant of Frontotemporal Dementia, or vascular dementia - Currently participating in a clinical trial
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Quality of life of patient and their caregiver | — |
Secondary
| Measure | Time frame |
|---|---|
| - Neuropsychiatric symptoms - Caregiver burden - Confidence mangaging neuropsychiatric symptoms - Psychotropic drug use - Cost-effectiveness - Feasibility of the intervention will be examined by the use of semi-structured interviews with a part of the patients and carergivers that underwent the intervention. | — |