Obesity, obesitas
Conditions
Interventions
none
Sponsors
University Medical Center Utrecht
Eligibility
Inclusion criteria
Inclusion criteria: • Healthy (self-reported) • Right-handed • Between 18 and 45 years old. • Having given their written informed consent
Exclusion criteria
Exclusion criteria: • Having a food allergy for any of the foods used as stimuli (i.e., ingredients of the milkshake and depicted on the food pictures) • Having a history of or current alcohol consumption > 28 units per week • Daily smoking • Having a history of medical or surgical events that may significantly affect the study outcome, such as metabolic or endocrine disease, or any gastro-intestinal disorder • Mental or physical status that is incompatible with the proper conduct of the study • Not having a general practitioner • Participation in any other clinical trial during this study. • MRI exclusion criteria, including o Claustrophobia o Presence of metal in body incompatible with MRI scanning o Being pregnant.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1.Neural activation (percentage signal change) in response to acquisition and extinction of cue-reward associations. 2.Neural activation (percentage signal change) in response to (un)healthy food choice. | — |
Secondary
| Measure | Time frame |
|---|---|
| 3. Scores on the liking of the food images and their perceived healthiness 4. Body weight at follow up. 5. Perceived temptation strength of the environment (ecological momentary assessment) 6. Cue reactivity | — |
Contacts
Public ContactP.A.M. Smeets
Outcome results
None listed