Central airways mechanics

Assessment of central airways mechanics using Magnetic Resonance Imaging (MRI) and bronchoscopy: a comparison

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON28602

Enrollment

Registered

2016-03-03

Start date

2016-06-01

Completion date

Unknown

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

tracheobronchomalacia (TBM) tracheabronchomalacie Central airway mechanics

Interventions

MRI

Eligibility

Inclusion criteria

Inclusion criteria: • Indication for bronchoscopy as decided by the treating paediatric chest physician; • Aged 6 years or above; • Ability to perform spirometry and spirometry controlled or technician controlled MRI • Informed consent from the parents / guardians.

Exclusion criteria

Exclusion criteria: • Any contraindications to MRI • In the case any contra indications to administering bronchodilator, this part of the protocol will be omitted

Design outcomes

Primary

Measure	Time frame
sensitivity and specificity of MRI as a diagnostic tool to assess central airway collapsibility	—

Secondary

Measure	Time frame
to assess concordance between MRI and bronchoscopy airway lumen reduction scores of both MRI and bronchoscopy to assess associations between MRI/ bronchoscopy scores and pulmonary function test (PFT) parameters	—

Contacts

Public ContactP. Ciet

Erasmus MC Sophia Childrens Hospital Department of Radiology and Paediatrics

Email: p.ciet@erasmusmc.nltel.: +31(0)10-7036467

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)