The variations in small vascular function and arterial compliance during the menstrual cycle in young healthy women.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON28594

Enrollment

Registered

2006-09-08

Start date

2006-10-23

Completion date

Unknown

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

geen, gezonde ovulerende vrouwen

Interventions

Microcirculatie meten door middel van microscoop van nagelbed (beoordelen van de refill na tijdelijke occlusie van de vinger) en iontoforese met Ach (endotheel afhankelijke-) en SNP (endotheel onafhan

Eligibility

Inclusion criteria

Inclusion criteria: 1. Healthy as judged by history and physical examination; 2. Regular ovulatory menstrual cycles between 21- 35 days (proven by biphasic BTC or midluteal progesterone > 10 nmol/l); 3. 18- 35 years; 4. no medication including oral conceptive or hormonal intra- uterine device (IUD) for at least three months; 5. Informed consent.

Exclusion criteria

Exclusion criteria: 1. Cardiovascular disease (hypertension (>160/90 mmHg), stroke, coronary artery disease,peripheral vascular disease, heart failure); 2. Diabetes mellitus (according to ADA criteria); 3. Smoking for the last three months; 4. Alcohol use > 4U/day; 5. Pregnancy; 6. Diseases that influence reproductive hormone status.

Design outcomes

Primary

Measure	Time frame
Microcirculatoire functie gemeten in 3 fasen van de cyclus (vroeg, laat folliculair en luteaal).	—

Secondary

Measure	Time frame
Bloeddruk.	—

Contacts

Public ContactI.J.G. Ketel

VU University Medical Center, Department of Reproductive Medicine (Poli H), P.O. Box 7057

ijg.ketel@vumc.nl+31 (0)20 4440041

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)