Chronic (>6months) ischemic stroke.
Conditions
Interventions
Single administration of 20 mg of fluoxetine, or placebo.
Sponsors
M.J. IJzerman
PO Box 310
7500 AH Enschede,
The Netherlands
Tel: (+31)534875700
Fax: (+31)534340849
m.ijzerman@rrd.nl
Eligibility
Inclusion criteria
Inclusion criteria: The participating patients suffered a single ischemic stroke (confirmed by CT-scan or MRI-scan) more than six months before the start of the trial, they were over 18 years of age. Furthermore, they were able to perform some selective movements with the paretic wrist (MRC 2). And were able to follow the intructions they were given.
Exclusion criteria
Exclusion criteria: 1. Patients suffering from an other neurological disease; 2. Uncompensated hemineglect or cognitive disabilities, resulting in misunderstanding or incapability of executing instructions given; 3. Epilepsy, or first epileptic insult poststroke; 4. Patients with first grade relatives suffering epilepsy; 5. Pregnancy; 6. Pacemaker; 7. State after irritation or lesion of median nerve; 8. Implanted pumps to administer medicines; 9. Metal parts inside the head; 10. Cerebral aneurysm-clips (metal inside); 11. Uncontrolled medical problems; 12. Alcoholism or drug-use; 13. Pathological heart rhythm disorders; 14. Raised intracerebral pressure (hydrocephalus); 15. External catheter.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Muscle activation patterns, measured by EMG. | — |
Secondary
| Measure | Time frame |
|---|---|
| Grip strength, Motricity Index, Delay times. | — |
Contacts
Public ContactH.I. Genderen, van
Roessingh Research and Development Rehabilitation Centre P.O. Box 310
Outcome results
None listed