glucose metabolism
Conditions
Interventions
Whole-body heat treatment
Sponsors
Maastricht University
Eligibility
Inclusion criteria
Inclusion criteria: In order to be eligible to participate in this study, a subject must meet all of the following criteria: • Signed informed consent • Men and women • Caucasian / white western European • Aged 40-70 years at the start of the study • Body mass index (BMI) 25-35 kg/m2 • Stable dietary habits (no weight loss or gain of more than 5 kg in the past 3 • months • Stable sedentary lifestyle (not more than 2 hours of sports per week) • Women after their menopause, meaning no menstrual cycle for at least 24 months and only if they are not under hormonal treatment. • Generally healthy, no medication use that interferes with metabolism. If volunteers need medication, it will be reviewed with the dependent physician on individual basis.
Exclusion criteria
Exclusion criteria: A potential subject who meets any of the following criteria will be excluded from participation in this study: • Haemoglobin 3kg in the past three months) • Participation in another biomedical study within 1 month prior to screening visit • Participants, who do not want to be informed about unexpected medical findings, or do not wish that their treating physician will be informed, cannot participate in this study • Blood donation three months prior to study and three months after finishing the study • Alcohol consumption of >2 servings per day Smoking in the past 6 months • Women if they don’t take oral contraceptives for at least 3 menstrual cycle
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| hepatic insulin sensitivity | — |
Secondary
| Measure | Time frame |
|---|---|
| substrate utilisation | — |
Contacts
Public ContactHannah Pallubinsky
Maastricht University
Outcome results
None listed