Recognizing patients with (a higher risk of) endometrial cancer; the role of fat distribution and inflammation in the origin of endometrial cancer, a study that focuses on prevention and prediction

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON28456

Enrollment

160

Registered

2021-07-23

Start date

2021-08-01

Completion date

Unknown

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Endometrial cancer

Interventions

Preoperatively: All included subjects are requested to consent for blood sample analysis, undergoing CT-scan and fill in three questionnaires. During surgery, fat tissue and (in cases) tumour tissue w

Eligibility

Inclusion criteria

Inclusion criteria: - CASES (n=80): - pre- and perimenopausal BMI =35 (n=20) - pre- and perimenopausal BMI 18-25 (n=20) - postmenopausal BMI =35 (n=20) - postmenopausal BMI 18-25(n=20)

Exclusion criteria

Exclusion criteria: - Other malignancy 40 years - pre- and perimenopausal BMI <25 (n=20) - postmenopausal BMI =35 (n=20) - postmenopausal BMI 18-25(n=20)

Design outcomes

Primary

Measure	Time frame
To compare hormone levels and inflammatory markers before and after BSO in obese and non-obese subjects.	—

Secondary

Measure	Time frame
To compare the effect of fat distribution and etiology on changes in hormone levels and inflammatory markers due to BSO in obese and non-obese subjects as well as the effect of BSO on menopausal complaints.	—

Contacts

Public ContactAnouk van den Bosch

MUMC

a.vdbosch@hotmail.com0630575778

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)