Muscle mass growth
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: • Healthy males • Age between 18 and 35 y inclusive • BMI between 18.5 and 30 kg/m2
Exclusion criteria
Exclusion criteria: • Allergies to milk proteins • Lactose intolerant • Smoking • Phenylketonuria • Diabetes Mellitus • Diagnosed GI tract disorders or diseases • Arthritic conditions • A history of neuromuscular problems • Any medications known to affect protein metabolism (i.e. corticosteroids, non-steroidal anti-inflammatories, or prescription strength acne medications). • Use of certain anticoagulants (use of thrombocyte aggregation inhibitors such as acetylsalicylic acid and carbasalaatcalcium is permitted. Use of other thrombocyte aggregation inhibitors will be discussed with the responsible physician) • Blood donation within 2 months of study initiation • Hypertension (according to WHO criteria) • Recent participation in amino acid tracer studies (less than 1 year ago)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| MPS and plasma AA availability | — |
Secondary
| Measure | Time frame |
|---|---|
| whole-body protein synthesis, breakdown, oxidation, and net balance, plasma glucose and insulin, and metabolic signalling | — |
Contacts
Maastricht University, Dep. Human Biology