Umbilical venous Infant Migration Thrombus formation Dutch: Navelvenelijn Pasgeborene Migratie Thrombusvorming
Conditions
Interventions
Case: Ultrasound on day 1, 3, 7 and 14 of catheter, the day of removing the catheter and whenever a chest X-ray is made on another day.
Control: Ultrasound on day 1, 7 and 14 after birth (or day of d
Sponsors
Leiden University Medical Center
Eligibility
Inclusion criteria
Inclusion criteria: • Study group: all infants receiving an umbilical venous catheter will be included (case). • Control group: For every included infant in the study group the next infant admitted to our ward without umbilical catheters will be included (control). • Matching case and control infants: o For cases ≥30 weeks gestational age we will match a control with the same gestational age at birth (+/- 1 week). o For cases < 30 weeks, matched controls are not available since all infants <30 weeks receive routinely umbilical catheters. For this group we will include infants without catheters with a gestational age of 30-32 weeks as controls.
Exclusion criteria
Exclusion criteria: None
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The frequency of thrombus formation in the umbilical venous catheter route or heart in infants with and without umbilical-vein catheters. | — |
Secondary
| Measure | Time frame |
|---|---|
| The amount of migrated umbilical venous catheters, the amount of umbilical venous catheters migrated to incorrect positions and the amount of umbilical venous catheters migrated to incorrect positions not detected by the chest X-ray made as standard of care. | — |
Contacts
Public ContactG.H. Dubbink-Verheij
LUMC Divison of Neonatology, Department of Pediatrics, J6-S
Outcome results
None listed