Reward sensitivity. Stress vulnerability. Healthy volunteers.
Conditions
Interventions
None listed
Sponsors
Maastricht University
Eligibility
Inclusion criteria
Inclusion criteria: 1. Aged between 18 – 35; 2. Sufficient command of the Dutch language to understand and give informed consent; 3. Mental competence*; 4. Signed informed consent; 5. Somatically, neurologically and mentally healthy state.
Exclusion criteria
Exclusion criteria: 1. Current Axis I diagnosis of psychiatric disorder or personality disorder; 2. Current alcohol or substance abuse; 3. Current psychotropic medication use.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| In the reward-learning paradigm, the main study parameter is the performance on the computerized task as measured by percentage correct choices of the rewarding stimulus relative to the losing stimuli. In both the ostracism and the social stress paradigms, the main study parameter is the change in stress scores endorsed by the participants on behavioural questionnaires, as a function of exposure to stressful stimuli. A parallel study parameter is the change in salivary cortisol concentrations as a function of exposure to the stress manipulation. | — |
Secondary
| Measure | Time frame |
|---|---|
| An additional study parameter is the change of stress scores from baseline (baseline) to multiple endpoints (immediately post-study, few hours post-study, the next day, etc) within each individual subject. | — |
Contacts
Public ContactZuzana Kasanova
P.O. Box 616
Outcome results
None listed