Relevance of circulating tumor cells in patients undergoing laparoscopic colon resection versus open resection; a randomized trial.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON28393

Enrollment

Registered

2005-09-06

Start date

2005-07-01

Completion date

Unknown

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colorectal cancer.

Interventions

Laparoscopic surgery compared to open surgery for colorectal cancer.

Eligibility

Inclusion criteria

Inclusion criteria: 1. Age between 40 and 80 years; 2. colorectal cancer including colon and rectosigmoid cancers; 3. informed consent.

Exclusion criteria

Exclusion criteria: 1. Prior midline laparotomy; 2. ASA III/IV; 3. Laparoscopic surgeon not available; 4. Prior upper and/or lower midline laparotomy; 5. Emergency colectomy; 6. Contraindications for epidural (coagulation disorders).

Design outcomes

Primary

Measure	Time frame
The amount of circulating tumor material induced by the surgical procedure, measured before, during and after the surgical procedure.	—

Secondary

Measure	Time frame
The level of cytokines before, during and after the surgical procedure. Differences in genotype between primary tumor and circulating tumor cells.	—

Contacts

Public ContactJ. Wind

Academic Medical Center (AMC), P.O. Box 22660

J.Wind@amc.uva.nl+31 (0)20 5663170

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)