Evaluatie van dynamische MRI als voorspeller van respons op behandeling in patienten met perianale fistels bij de ziekte van Crohn.

Evaluation of the predictive value of Dynamic MRI in determining treatment response in perianal fistulizing Crohn’s disease before and after treatment.

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON28234

Enrollment

Registered

2009-09-01

Start date

2008-07-07

Completion date

Unknown

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Crohn, perianal fistula, perianale fistel.

Interventions

MRI before start therapy, after 12 weeks, after one year.

Eligibility

Inclusion criteria

Inclusion criteria: 1. Crohn's disease; 2. Draining perianal fistula; 3. Starting with therapy for perianal fistula.

Exclusion criteria

Exclusion criteria: 1. Age < 18 years; 2. Contraindications for MRI (pregnancy, renal insufficiency, allergy to contrast media, metallic implants).

Design outcomes

Primary

Measure	Time frame
Predictive value of DCE-MRI before treatment and during treatment (12 weeks) in predicting or identifying early response as compared to the PDAI (12 weeks).	—

Secondary

Measure	Time frame
Predictive value of DCE-MRI compared to the MRI-based score, CRP.	—

Contacts

Public ContactM.L.W. Ziech

Meibergdreef 9

m.l.ziech@amc.uva.nl+31 (0)20 5663740

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)