Prostate Cancer
Conditions
Interventions
All biopsies will be taken in the left lateral decubitus position.
Group 1:
8 ultrasound-guided transrectal biopsies, laterally aimed in the peripheral zone: one from the apex, two from the middle a
Sponsors
AMC, department of Urology, Amsterdam, the Netherlands
Eligibility
Inclusion criteria
Inclusion criteria: 1. Age 1,24 ng/ml 2. Age > 49 2,24 ng/ml 3. Age > 59 2,24 ng/ml 4. Age >69 and PSA > 3,24 ng/ml 5. Abnormal DRE 6. Abnormal TRUS
Exclusion criteria
Exclusion criteria: 1. Age < 18 2. Proven prostate cancer 3. Clinical prostatitis < 1 month ago 4. Acute urinary retention < 1 month ago 5. PSA altering medicine (finasteride, dutasteride) used in the last 6 months
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| - How do the primary outcomes relate to patient characterisics such as age, PSA, PSA-ratio, complexed PSA, symptoms. - How many more complications occur in a 12 biopsy-protocol compared to an 8- biopsy protocol. | — |
Primary
| Measure | Time frame |
|---|---|
| - How many prostate cancers are found using a 12-biopsy protocol compared to an 8-biopsy protocol. - How many cancers are found in repeated biopsies after using a 12-biopsy protocol compared to an 8-biopsy protocol - What % of cancers is found in the transition zone only in repeated biopsies after using a 12-biopsy protocol compared to an 8-biopsy protocol | — |
Contacts
Public ContactS.A. Zaaijer
Academic medical Center (AMC) Department of Urology P.O. Box 22660
Outcome results
None listed