Progesterone supplementation in natural cycles improves live birth rates after embryo transfer of frozen-thawed embryos—a randomized controlled trial

Studier om hur resultaten påverkas av progesteronsubstitution i lutealfas vid frysåterföring i naturlig cykel, efter tidigare genomgången IVF-behandling

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON28205

Enrollment

500

Registered

2013-12-05

Start date

2013-02-01

Completion date

Unknown

Last updated

2024-06-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

luteal support, progesterone, frozen embryo transfer, natural cycle

Interventions

The treatment (intervention) is substitution with vaginal tablets of Lutnius (progesterone) 100 mg two times daily, started on the day of embryo transfer and continued until 8 weeks of pregnancy, comp

Eligibility

Inclusion criteria

Inclusion criteria: Patients planning frozen embryo transfer in a natural cycle

Exclusion criteria

Exclusion criteria: Patient who do not want to participate. Adverse effect of Lutinus.

Design outcomes

Primary

Measure	Time frame
Live born child	—

Secondary

Measure	Time frame
Prennancy rate, ongoing pregnancy rate, misscarriage rate. Serum levels of progesterone and cytokines	—

Contacts

Public ContactKjell Wånggren

Associate Professor Dept of Womens and Childrens Health, Uppsala Universty.

kjell.wanggren@kbh.uu.se

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)