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The AIMS study.

Theory- and evidence-based intervention to improve adherence to antiretroviral therapy among HIV-infected patients: the AIMS study.

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
NL-OMON
Registry ID
NL-OMON28192
Enrollment
200
Registered
2005-09-01
Start date
2005-09-01
Completion date
Unknown
Last updated
2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

HIV infection

Interventions

After a baseline period of 2 months during which adherence is registered using MEMS-caps, patients are randomized to receive the AIMS-intervention or not. Next, the AIMS intervention starts, and aft

Sponsors

Department of Internal Medicine, Division of Infectious Diseases, Tropical Medicine and AIDS, Academic Medical Center, Amsterdam, the Netherlands Department of Experimental Psychology, Faculty of Psychology, Maastricht University, the Netherlands and Department of Health Education and Promotion, Faculty of Health Sciences, Maastricht University, the Netherlands
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. HIV-1 positive, using HAART. 2. Treatment experience for at least 6 months, with a maximum of 5 years; 3. Sufficient knowledge of the English or Dutch language (verbal and in writing); 4. No current psychiatric, drug or alcohol problems; 5. More or less stable housing; 6. Able to give informed consent.

Exclusion criteria

Exclusion criteria: N/A

Design outcomes

Primary

MeasureTime frame
1. The primary purpose of the proposed study is to investigate whether or not adherence to HAART can be significantly increased by HIV-nurses using the AIM-Strategy, and whether this is sustained over time; 2. Whether or not these improvements result in a decrease of intracellular HIV-RNA.

Secondary

MeasureTime frame
1. Furthermore, a questionnaire will be used to see which cognitive variables of the patients are related to (non)adherence and to evaluate whether or not the intervention successfully changes those cognitive variables that cause non-adherence; 2. Finally, a process evaluation will be conducted among patients, HIV-nurses and physicians to investigate the advantages (e.g., insight in adherence, detection of treatment problems, improved communication) and disadvantages (e.g. duration intervention sessions, user-friendliness of equipment) of the use of AIMS versus providing standard care.

Contacts

Public ContactJ.M. Prins

Academic Medical Center (AMC), Department of Internal Medicine, F4- 217, P.O. Box 22660

j.m.prins@amc.uva.nl+31 (0)20 5664380

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)