the Application of Exhaled breath aNalysis in the Early detection of ASpergillosis

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON28185

Enrollment

Registered

2020-07-06

Start date

2020-09-01

Completion date

Unknown

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Invasive aspergillosis

Interventions

Exhaled breath sampling.

Eligibility

Inclusion criteria

Inclusion criteria: Patients, aged 18 or older, that will undergo treatment for a hematological malignancy expected to result in grade 4 neutropenia for more than 7 days, e.g. hematopoietic stem cell transplantation or induction/consolidation treatment for acute myeloid leukaemia.

Exclusion criteria

Exclusion criteria: Previous invasive pulmonary mycosis.

Design outcomes

Primary

Measure	Time frame
The accuracy with which patients with probable or proven invasive pulmonary aspergillosis and neutropenic controls can be discriminated from each other with exhaled breath analysis using among other techniques GC-MS, as measured by the values of the sensitivity, specificity and accuracy.	—

Contacts

Public ContactKoen de Heer

AUMC

k.deheer@amsterdamumc.nl020-5669111

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)