severe acute respiratory infection, surveillance, influenza, hospital admission, ernstige acute luchtweg infectie, ziekenhuisopname, SARI
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: A SARI patient will be defined as a hospitalised person with: •at least one systemic symptom or sign: fever or feverishness, malaise, headache or myalgia or deterioration of general condition (asthenia or loss of weight or anorexia or confusion or dizziness) v and •at least one respiratory symptom or sign (cough, sore throat or shortness of breath) at admission or within 48 hours after admission.
Exclusion criteria
Exclusion criteria: The symptoms of onset should not have started (or clearly worsened, if chronic) more than 7 days at admission
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The development and establishment of a sustainable SARI surveillance system that, when this is proven feasible, will be extended to other hospitals from the year 2019 onward. The end result is an integrated respiratory surveillance system covering the full spectrum of respiratory infections, which provides input for (inter)national public administrations and is used for policy decisions. The planned products are: •Protocol for the implementation of a potential nationwide sustainable continuous SARI surveillance; •Weekly publication of the results of fully integrated respiratory surveillance system on RIVM website. | — |
Secondary
| Measure | Time frame |
|---|---|
| •Seasonal influenza vaccine effectiveness against influenza laboratory confirmed SARI hospitalisation among patient 65 years of age and above. •Data used for pooling with 22 hospitals in other European countries to obtain robust data on influenza vaccine effectiveness against severe outcomes. •Amount of SARI patients attributable to influenza and/or other causative respiratory pathogens per influenza season. •The disease burden of influenza on different health care levels. | — |
Contacts
Centre for Epidemiology and surveillance of infectious diseases Centre for Infectious disease control (CIb) National Institute for public health and the Environment (RIVM)